Our Team

OUR TEAM

R Venkataramanan

R Venkataramanan

Director
R Venkataramanan

R Venkataramanan

Director

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Venkat is Founder and CEO of Karkinos Healthcare. He is currently engaged as an Advisor to the Chairman, Reliance Industries Limited, India's largest private sector company.

Prior to his association with Reliance, Venkat spent more than a decade and a half with the Tata Group in various capacities. His last assignment in the Tata Group was as Managing Trustee of the Tata Trusts wherein he was responsible for the operations, oversight and co-ordination between the various Tata Trusts.

In his role as the Chief Executive Officer of the Tata Trusts, Venkat was engaged in redefining the Tata Trusts' strategic approach with a view to making it relevant and responsive to the current needs of society while remaining within the mandate established by the Settlors. He was directly overseeing several large initiatives within the Trusts viz "Lakhpati Kisan – an program that aims to significantly enhance rural prosperity in under privileged and deprived communities, redefining Cancer Care across the country, technology enabled education initiatives in partnership with Massachusetts Institute of Technology (MIT) and the sanitation and nutrition projects in collaboration with Govt., of India.

He has over two decades of business and operations experience in the areas of finance, business support and strategy. From early 2007 to end 2012, he was Executive Assistant to Mr. Ratan N. Tata, the former Chairman of the Tata Group. During his stint in the Chairman's office of Tata Sons, Venkat was part of several significant projects including the Tata Motors acquisition of Jaguar Land Rover, launch of the small car Nano, creation of several Joint Ventures, responses in operating companies during the 2008 financial crisis etc., and was also privy to several senior leadership transitions and change management processes in the Tata Group. On behalf of the Chairman, he was the key point person to several entities in India and abroad.

Prior to his stint with Mr. Tata's office, Venkat was associated as Head of Business Support at the Qatar Foundation, a not for profit entity engaged in Education, Science and Community development based in Doha, wherein he played a key role in establishing partnerships with a number of leading US universities.

Venkat is a Science graduate and has done his MBA from the Sri Satya Sai University, Puttaparthi. He is also a Law Graduate from Mumbai University and has completed his Advanced Management Program (AMP) from the Harvard Business School. He is currently pursuing his EngD from the University of Warrick, UK on role of Technology in Health Care Systems.

Over the past several years, in his personal capacity, Venkat actively supported Mr. Ratan Tata in his investments in the technology, digital and e-commerce space that have now begun to attract significant attention in India and abroad. He was also the CEO of UC-RNT Fund, a US$ 350 million VC fund that Mr. Tata established in collaboration with the University of California. A key proponent of societal platforms, he is the midst of incubating alternative business and investment vehicles that work in the intersection of business, philanthropy, non-profits and governments on the notion of sustainable shared value creation for societal benefit

  1. Advisor to Chairman, Reliance Industries Ltd
  2. Chief of Staff to Chairman, Tata Sons and Managing Trustee of Tata Trusts
  3. Tata Memorial Hospital and Tata Medical Centre Trust, conceived Tata Centers for cancer care
  4. CEO and Partner of UC-RNT Fund and RNT Capital Advisors, a $350 million fund
Dr. Moni Abraham K.

Dr. Moni Abraham K.

Clinical Director
Dr. Moni Abraham K.

Dr. Moni Abraham K

Clinical Director

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Co-Founder, Medical Director and CEO, Karkinos Kerala

BSC, BDS, MB CHB, MD (USA), FDSRCS, FFDRCS, FRCS, FRCS ED, AB

Moni Abraham Kuriakose has previously served Narayana Health City, Bangalore as director of surgical oncology and director of Mazumdar Shaw Centre for Translational Research. Prior to this he had the following assignments-

  1. Chairman of Head and Neck Institute, Amrita Institute of Medical Sciences, Cochin,
  2. Attending Surgeon, and Professor, New York University,
  3. Professor and Vice Chairman Head and Neck Oncology and Director of Research, Roswell Park Cancer Institute, New York.

He is currently visiting professor at Roswell Park Cancer Institute and New York University. His clinical interests are management of advanced head and neck cancer, skull-base surgery, 3D planning and functional reconstruction. His research laboratory focus on understanding biology of oral cancer stem cells and targeting it to prevent oral cancer and using novel technology platform for early detection of the cancer. He has over 200 peer reviewed publications and five international patents to his credit. He is the author of a four-volume textbook titled `Contemporary Oral Oncology' and the Editor-in-Chief of the journal "Oral Cancer" by Springer-Nature group. He has served Indian head and neck cancer society (FHNO) as its past president and is the President Elect of International Academy of Oral Oncology (IAOO).

  1. Ex-Director, Surgical Oncology, Narayana Health City and ex-Director of Mazumdar Shaw centre for translational research
  2. Attending Surgeon and Professor at New York University; has 200 peer reviewed publications and 5 international patents
  3. Professor and Vice-Chairman, Head and Neck Oncology and Director of Research, Roswell Park Cancer Institute, New York
  4. President-elect of International Academy of Oral Oncology (IAOO) and Ex-President of Indian head and neck cancer society (FHNO)

Selected peer-reviewed publications

  1. P Mendonca, et al., Non-invasive imaging of oral potentially malignant and malignant lesions: A systematic review and meta-analysis, Oral Oncology 130, 105877, 2022.
  2. SJ Ma, H Yu, et al, Evaluation of Optimal Threshold of Neutrophil-Lymphocyte Ratio and Its Association With Survival Outcomes Among Patients With Head and Neck Cancer, JAMA Network Open 5 (4), e227567-e227567, 2022
  3. Iovoli AJ, et al. Among authors: Kuriakose MA. Association of Nonsteroidal Anti-inflammatory Drug Use With Survival in Patients With Squamous Cell Carcinoma of the Head and Neck Treated With Chemoradiation Therapy. JAMA Network Open. 2020.
  4. Mehanna H, et al. Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus. Lancet Oncol. 2020 Jun 11:S1470-2045(20)30334-X.
  5. Sivadasan P, et al. Salivary proteins from dysplastic leukoplakia and oral squamous cell carcinoma and their potential for early detection. J Proteomics. 2020 Feb 10;212:103574.
  6. Sumsum Sunny, et al. A smart tele-cytology point-of-care platform for oral cancer screening PLoS One. 2019; 14(11): e0224885
  7. Kulsum S, et al. Cancer stem cells and fibroblast niche cross talk in an in-vitro oral dysplasia model. Mol Carcinog. 2019 May;58(5):820-831. doi: 10.1002/mc.22974. Epub 2019 Jan 31.PMID: 30644602.
  8. Anurag K. Singh, et al. Combined surgery and radiation improves survival of tonsil squamous cell cancers. Oncotarget 08/2017; 8(68)
  9. Gangotri Siddappa, et al,. Curcumin and metformin mediated chemoprevention of oral cancer is associated with inhibition of cancer stem cells. Mol Carcinog 06/2017; 56(11)., DOI:10.1002/mc.22692
  10. Bhat AR, Gupta MK, Krithivasan P, Dhas K, Nair J, Reddy RB, Sudheendra HV, Chavan S, Vardhan H, Darsi S, Balakrishnan L, Katragadda S, Kekatpure V, Suresh A, Tata P, Panda B, Kuriakose MA, Sirdeshmukh R. Sample preparation method considerations for integrated transcriptomic and proteomic analysis of tumors Proteomics Clin Appl. 2017 Mar;11(3-4). doi: 10.1002/prca.201600100. Epub 2016. Nov 28. PMID: 27801551.
Dr. Prashant Kumar

Dr. Prashant Kumar

Research Director
Prof Rita Isaac

Prof Rita Isaac

Director of Population Research
Prof Rita Isaac

Prof Rita Isaac

Director of Population Research

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Rita Isaac, Director of Population Research, Karkinos Health Care & Former Senior Professor at Christian Medical College, Vellore is an internationally recognized expert in cervical cancer prevention and control in low resource settings in India. For more than 2 decades, she has been devoted to establishing models of care in low resource settings for non-communicable diseases with special focus on cervical and oral Cancer and also diabetes and chronic respiratory diseases through translational research in collaboration with international universities and organisations. She has extensively researched community factors that facilitate or hinder cervical cancer screening uptake and significance of stakeholders’ engagement in rolling out effective cancer screening programme in low resource settings. She currently leads the implementation science research at Karkinos Healthcare Pvt Ltd. Mumbai, India. She also directs community cancer outreach programs for underserved populations in the service area of the organisation.

As faculty at Christian Medical College, Vellore, India, her research focused on developing cancer screening strategies and ensuring their effectiveness in resource limited settings. For equity and promotion of early detection of cancer and other non-communicable diseases, she has adopted the strategies like decentralized cancer/NCD care, task shifting to trained frontline health workers to engage the communities and serve as patient navigators which has revolutionized patient care and reduced health disparities. She has championed efforts to decrease smoking and implement other cancer risk reduction programs, as well as to provide critical support to cancer patients and concentrate on cancer control efforts in areas where they could be most effective.

Dr. Ajit Nambiar

Dr. Ajit Nambiar

Senior Clinical Scientist
Dr. Ajit Nambiar

Dr. Ajit Nambiar

Senior Clinical Scientist

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Dr. Ajit Nambiar, MD DNB FRCPath (UK), Fellowship in Surgical Oncopathology (TMH)

Dr. Ajit Nambiar Trained at Tata Memorial Hospital (TMH) and Imperial Trust, UK. He is an Ex Prof. & HOD Pathology, Amrita Institute of Medical Sciences, Kochi.

Dr. Ajit has expertise in the fields of onco-pathology, histopathology, cytopathology and Molecular pathology with Breast and Lung as Lead areas.

As part of his experience Dr. Ajit has successfully established six sigma lab processes, automation of IHC labs, coagulation labs, Digital Pathology and molecular laboratories as HOD, Amrita Institute of Medical Sciences, Kochi. On the academic front the department could commence with Fellowship courses in Oncopathology, Renal Pathology and GI Liver under his leadership. Dr. Ajit also organised 4 AAPUD (amrita annual pathology update) International Pathology event from 2017 to 2021, state IAPM meet 2019, National IAPM on Minimalistic Pathology conference 2019, AIPNA 2021 and 24 webinars series SAGE with eminent national international GURU'S in Pathology.

Dr. Ajit has published 40 articles in National and International Journals and is a reviewer for 5 journals.

Dr. Ajit is the Trainer of trainers for Roche Merck PDL1 assays and also the Medical advisory board , Pathology for Roche and Merck.

Selected peer-reviewed publications (Dr. Ajit)

  1. Ragima Nadesh et al. Adipose derived mesenchymal stem cell secretome formulation as a biotherapeutic to inhibit growth of drug resistant triple negative breast cancer. December 2021. Nature Scientific Reports 11(1):23435
  2. Anish A Mohan eta l. EGFR analysis on scrapings from cytology smears in lung carcinoma, an effective alternative to testing on trucut biopsies. Diagnostic cytopathology Volume49, Issue10 October 2021Pages 1155-1163.
  3. Narayana Subramaniam et al. Low PDL1 Expression in Tumour Infiltrating Lymphocytes Predicts Local Recurrence in Oral Squamous Cell Carcinoma. Indian Journal of Surgical Oncology. April 2021.
  4. Dimpy Sharma et al. Evaluation of Antigenicity of Components of Tracheal Allotransplant and Effect of Immunosuppressant Regime in a Rodent Model. Ind J of Plastic Surgery 2020: 53;357
  5. e) Narayana Subramaniam et a. Lymph node staging systems in oral squamous cell carcinoma: A comparative analysis. Oral Oncology October 2019
  6. Narayana Subramaniam et al. Predictors of locoregional control in stage I/II oral squamous cell carcinoma classified by AJCC 8th edition. European Journal of Surgical Oncology, Volume 45, Issue 11, 2126 – 2130 May 2019
  7. Samskruthi Murthy et al. Validation of the eighth edition AJCC staging system in early T1 to T2 oral squamous cell carcinoma. J Surg Oncol.2018;1‐6.
  8. Ajit Nambiar, Sunil Pv, Vijaylakshmi Susheelan, Moni Abraham Kuriakose. The Concepts in Poorly Differentiated Carcinoma of the Thyroid: A Review Article. Journal of Surgical Oncology. 2011;103:818–821
  9. i) Ajit Nambiar. A hospital-based audit on surgical reporting of Low anterior resection of rectal cancers. Ind. J of cancer. April–June 2010. Volume 47, Issue 2 Pg 156-159
  10. Ajit Nambiar. The Trail of carpet bombing" – Acute radiation colitis in patient's treated with short term preoperative radiotherapy for rectal cancers: An Indian Experience Modern Pathology. 2006; vol 19, supplement 3 : 66-67.
Dr. Prerana Jha

Dr. Prerana Jha

Senior Research Scientist
Dr. Prerana Jha

Dr. Prerana Jha

Senior Research Scientist

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Dr. Prerana Jha, PhD in molecular oncology brings a vast experience of more than 15 years in the field of cancer research. She received her training at All India Institute of Medical Sciences, New Delhi and Comprehensive Cancer Center, Ohio State University, USA. She has a clear understanding of basic biology, advanced genomic techniques and has been continuously involved in implementation of continually upgrading technology in precision medicine. Her work has been recognized consistently through first author and several coauthor publications in high-impact oncology journals

Selected peer-reviewed publications

  1. Singh J*, Dandapath I*, Jha P*, et al. Gene expression-based profiling of pleomorphic xanthoastrocytoma highlights two prognostic subgroups. American Journal of translational Research. 2022 Feb 15;14(2):1010-1023. [* Equivalent authors]
  2. Dandapath* I, Gupta R*, Singh J, Shukla N, Jha P, Sharma V, Suri A, Sharma MC, Suri V, Sarkar C, Kulshreshtha R. Long non-coding RNA and mRNA co-expression network reveals novel players in pleomorphic xanthoastrocytoma. Mol Neurobiol. 2022 Jun 8.doi: 10.1007/s12035-022-02893-5. Online ahead of print.
  3. Manjunath N*, Jha P*, Singh J, Sarkar C, Mohan M, Mani K, Suri V. Clinico‑pathological and molecular characterization of diffuse midline gliomas: is there a prognostic significance? Neurol Sci 2020 Jul 14 [* Equivalent authors]
  4. Jha P, Manjunath N, Singh J, Garg A, Kaur K, Sharma MC, Suri A, Sarkar C, Suri V. Analysis of PDL1 expression and T cell infiltration in different molecular subgroups of diffuse midline gliomas. Neuropathology. 2019 Dec;39(6):413‑424.
  5. Kaur K, Jha P, Pathak P, Suri V, Sharma MC, Garg A, Suri A, Sarkar C. Approach to molecular subgrouping of medulloblastomas: Comparison of NanoString nCounter assay versus combination of immunohistochemistry and fluorescence in‑situ hybridization in resource constrained centres. J Neurooncol. 2019 Jul;143(3):393-403.
Dr. Sindhu

Dr. Sindhu

Senior Research Scientist
Dr. Sindhu

Dr. Sindhu

Senior Research Scientist

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Sindhu Govindan, is a passionate cancer biologist with a PhD in head and neck oncology and has been in the field of clinical translation of cancer research for more than a decade. She has over 18 years of experience in tissue banking, molecular diagnostics, ex vivo tumor culture systems, biomarker identification, quality management system in medical devices and laboratories, validation and assay development in oncology. Her core expertise is in gene expression panel development for resistance/response, clinical and experimental data analysis, Immunohistochemistry, primary cell culture and in vitro cell stem assays. She has played a pivotal role in the validation and marketing of Can-Assist Breast test developed at OncoStem Diagnostics, Bangalore. As a Senior Scientist and Team Lead in Farcast Bioscience, Bangalore, she was responsible for delivering NS assay, cytokine, flowcytometry and STR assay reports to biopharma clients. He is an expert in setting up and managing molecular, and cell culture labs. She has 14 publications in reputed International Journals. Ramesh heads Biobank and Cancer biology lab at Karkinos Healthcare.

Selected peer-reviewed publications (Dr. Sindhu)

  1. Govindan, S., Siraganahalli Eswaraiah, M., Basavaraj, C. et al. Androgen Receptor mRNA levels determine the prognosis in triple-negative breast cancer patients. BMC Cancer 20, 745 (2020).
  2. Thomas D, Govindan S, Baiju EC et al. Cyperus rotundus L. prevents non-steroidal anti-inflammatory drug-induced gastric mucosal damage by inhibiting oxidative stress. J Basic Clin Physio Pharmacol. 2015; 26 (5).
  3. Vikkath N, Valiyaveedan S, Nampoothiri S, et al.,Genotype-phenotype analysis of von Hippel-Lindau syndrome in fifteen Indian families. Fam Cancer. 2015; 14 (4).
  4. Surendran S, Siddappa G, Mohan A et al. Cancer stem cell and its niche in malignant progression of oral potentially malignant disorders. Oral Oncol. 2017 Dec;75:140-147.
  5. Narayana Subramaniam et a. Lymph node staging systems in oral squamous cell carcinoma: A comparative analysis. Oral Oncology October 2019
Dr. Prasanth Ariyannur

Dr. Prasanth Ariyannur

Senior Research Scientist
Dr. Prasanth Ariyannur

Dr. Prasanth Ariyannur

Senior Research Scientist

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Dr. Prasanth Ariyannur is the head of clinical genomics laboratory at Karkinos Advanced Cancer DIagnostics and Research (ACCDR) Laboratory at Kochi. He got his MBBS from Govt. Medical College Thiruvananthapuram and MD in Clinical Biochemistry and laboratory medicine from Amrita School of Medicine. In 2004, he went for graduate studies and trained in Uniformed Services University of Health Sciences (USUHS), Bethesda Maryland USA. His training was in molecular neurobiology on addiction physiology, neuronal energetics and tryptophan mediated immune tolerance in the US National Capital Consortium, the US National Institute of Health and USUHS. He has identified and characterized the gene responsible for aspartyl N-acetyltransferase function in the brain and generated transgenic animal models for studying the biobehavioral effects in 2011. During the last decade, Dr. Prasanth has been instrumental in establishing research projects to understand the genotype and phenotype correlation of many hereditary cancers such as Neurofibromatosis and other RASopathies, hereditary breast and ovarian cancers and hereditary colon cancers in Amrita Institute of Medical Sciences, Kochi Kerala. He established a diagnostic molecular oncology laboratory in Amrita Institute, Kochi. He has been actively involved in somatic mutation identification and constantly improving the genomic analysis methods in cancers occurring in lung, breast, prostate, colon, thyroid and endometrium. He has developed many novel laboratory tests in Amrita Institute which got national and international quality accreditations. He has 35 publications in international journals on basic science research, along with review articles and book chapters. He is also a principal Investigator of a project funded by ICMR.

Selected peer-reviewed publications (Dr. Prasanth Ariyannur)

  1. Ariyannur PS, Joy R, Menon V, Paulose R, Pavithran K, Vasudevan DM. An approach to compare Nanostring PanCancer pathway analysis with TCGA data for colon adenocarcinoma in the South Indian population: A pilot study. Ecancermedicalscience 2021;15 1302. PMID: 34824625.
  2. Mohan AA, Vallonthaiel AG, Nambiar A, Ariyannur P, Joy RA, Thelakkattusserry SK, Vikkath N, Joseph T, Mehta A, Perathur A. EGFR analysis on scrapings from cytology smears in lung carcinoma, an effective alternative to testing on trucut biopsies. Diagn Cytopathol. 2021, 49(10):1155-1163. PMID: 34432954.
  3. Paul A, Pai, PG, Ariyannur PS, Joy RA. Diagnostic accuracy of MicroRNA 208b level with respect to different type of atrial fibrillation. Indian Heart J 2021, 73(4):506-510. PMID: 34474768
  4. Joy RA, Thelakkattusserry SK, Vikkath N, Bhaskaran R, Vasudevan D, Krishnan S, Ariyannur PS. Somatic mutation detection efficiency in EGFR: a comparison between High Resolution Melting Analysis and Sanger Sequencing. BMC Cancer, 2020 September 22;20(1):902. PMID: 32962681.
  5. Vikkath, N, Ariyannur PS, Menon KN, Bindhu MR, Pillai A., Exploring the role of defective fibronectin matrix assembly in the VHL-associated CNS hemangioblastoma. Drug Metabolism and Personalized Therapy., 2018 September;33(3):127-134. PMID: 29813026 .
Dr. Ruma Pengal

Dr. Ruma Pengal

Senior Research Scientist
Dr. Ruma Pengal

Dr. Ruma Pengal

Senior Research Scientist

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Dr. Ruma Pengal has a background in cellular biology with a keen interest in signal transduction pathways. She has worked on research projects involving signalling in innate immune cells and kinase pathways involved in cellular injury.

Selected peer-reviewed publications (Ruma)

  1. Nie X, Chanley MA, Pengal R, Thomas DB, Agrawal S, Smoyer WE. Pharmacological and genetic inhibition of downstream targets of p38 MAPK in experimental nephrotic syndrome. Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F602-F613. doi: 10.1152/ajprenal.00207.2017.
  2. Guess AJ, Ayoob R, Chanley M, Manley J, Cajaiba MM, Agrawal S, Pengal R, Pyle AL, Becknell B, Kopp JB, Ronkina N, Gaestel M, Benndorf R, Smoyer WE. Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis. PLoS One. 2013;8(1):e54239. doi: 10.1371/journal.pone.0054239
  3. Pengal R, Guess AJ, Agrawal S, Manley J, Ransom RF, Mourey RJ, Benndorf R, Smoyer WE. Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury. Am J Physiol Renal Physiol. 2011 Sep;301(3):F509-19.
  4. Pengal RA, Ganesan LP, Wei G, Fang H, Ostrowski MC, Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol Immunol. 2006 Apr;43(10):1557-64.
  5. Fang H, Pengal RA*, Cao X, Ganesan LP, Wewers MD, Marsh CB, Tridandapani S. Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP. J Immunol. 2004 Jul 1;173(1):360-6 (*- Co-first author)
Dr. Ruma Pengal

Dr. Srikanth

Senior Clinical Scientist
Dr. Ruma Pengal

Dr. Srikanth

Senior Clinical Scientist

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Dr. Srikanth has completed his Master’s in biotechnology from Indian Institute of Technology, Bombay, India and thereafter, pursued a Ph.D. in Bioinformatics from Institute of Bioinformatics, Bangalore, India and Johns Hopkins University, Baltimore, USA. He has an extensive experience of more than a decade in analysis and interpretation of data from large-scale cancer genomics, transcriptomics and proteogenomics projects. He has co-authored more than thirty research articles in journals of international reputation in the field of multi- omics, including publications in Nature, Nature Methods, Genome Research, Nature comm., and MCP, among others and is also a reviewer for eight international journals.

Dr Srikanth worked as a Cancer Data scientist in Procan® at Children’s Medical Research Institute, Australia for several years before joining Karkinos Healthcare Pvt Ltd. Working at Procan®, Australia’s and world’s first initiative Dr. Srikanth worked on analysing large-scale proteogenomic datasets from adult and childhood cancers to identify potential biomarkers and therapeutic targets.

As a Research Scientist at Syngene International Pvt. Ltd. he has worked on several metagenomics and transcriptomics projects. Dr. Srikanth also worked with LifeBytes Pvt. Ltd. as a computational biologist to develop WGS, WES, and single cell omics data analysis pipelines for several clients in India and US.

Dr. Srikanth is currently the head of computational biology group at Karkinos and interests in multi-omics data analysis, integration and interpretation of Big Data from genomics, transcriptomics, epigenomics and proteomics.

Publications (Total: 33) H-index=25, Total Citations 4,342

  1. Gonçalves, E., Poulos, R. C., Cai, Z., Barthorpe, S., Manda S. S., Lucas, N., Beck, A., Bucio-Noble, D., Dausmann, M., Hall, C., Hecker, M., Koh, J., Lightfoot, H., Mahboob, S., Mali, I., Morris, J., Richardson, L., Seneviratne, A. J., Shepherd, R., Sykes, E., Thomas, F., Valentini, S., Williams, S. G., Wu, Y., Xavier, D., MacKenzie, K. L., Hains, P. G. , Tully, B., Robinson, P. J., Zhong, Q., Garnett, M. J., Reddel, R. R. (2022). Pan-cancer proteomic map of 949 human cell lines. Cancer Cell, 40, 835-849
  2. Manda, S. S., Noor, Z., Hains, G. P and Zhong, Q (2021). PIONEER: Pipeline for generating High-quality Spectral libraries for DIA-MS Data. Current Protocols in Bioinformatics. e69.
  3. Logan, J., Pearson, M. S., Manda, S. S, Choi, Y.J, Field, M., Eichenberger, R.M., Mulvenna, J., Nagaraj, S.H., Fujiwara, R.T., Gazzinelli-Guimaraes, P., Bueno, L., Mati, V., Bethony, J.M., Mitreva, M., Sotillo, J. and Loukas, A. (2020) Comprehensive analysis of the secreted proteome of adult Necator americanus hookworms. PLoS Negl Trop Dis. 14(5):e0008237.
  4. Poulos, R.C., Hains, P.G., Shah, R., Lucas, N., Xavier, D., Manda, S. S, Anees, A., Koh, J.M.S., Mahboob, S., Wittman, M., Williams, S.G., Sykes, E.K., Hecker, M., Dausmann, M., Wouters, M.A., Ashman, K., Yang, J., Wild, P.J., DeFazio, A., Balleine, R.L., Tully, B., Aebersold, R., Speed, T.P., Liu, Y., Reddel, R.R., Robinson, P.J. and Zhong, Q. Strategies to enable large-scale proteomics for reproducible research. Nat Commun. 2020 Jul 30;11(1):3793.
  5. Manda, S. S., Nirujogi, R. S., Pinto, S. M., Kim, M. S., Datta, K. K., Sirdeshmukh, R., Prasad, T. S., Thongboonkerd, V., Pandey, A., and Gowda, H. (2014) Identification and characterization of proteins encoded by chromosome 12 as part of chromosome-centric human proteome project. Journal of proteome research 13, 3166-3177
  6. Manda, S. S. #, Mirsafian, H. #, Mitchell, C.J., Sreenivasamurthy, S., Ripen, A. M., Mohamad, S. B., Merican, A. F. and Pandey, A. (2016) Long non-coding RNA expression in primary human monocytes. Genomics. S0888-7543(16)30002-7. # (Equal contribution)
  7. Pinto, S. M., Manda, S. S., Kim, M. S., Taylor, K., Selvan, L. D., Balakrishnan, L., Subbannayya, T., Yan, F., Prasad, T. S., Gowda, H., Lee, C., Hancock, W. S., and Pandey, A. (2014) Functional annotation of proteome encoded by human chromosome 22. Journal of proteome research 13, 2749-2760
  8. Kim, M. S., Pinto, S. M., Getnet, D., Nirujogi, R. S., Manda, S. S., Chaerkady, R., Madugundu, A. K., Kelkar, D. S., Isserlin, R., Jain, S., Thomas, J. K., Muthusamy, B., Leal-Rojas, P., Kumar, P., Sahasrabuddhe, N. A., Balakrishnan, L., Advani, J., George, B., Renuse, S., Selvan, L. D., Patil, A. H., Nanjappa, V., Radhakrishnan, A., Prasad, S., Subbannayya, T., Raju, R., Kumar, M., Sreenivasamurthy, S. K., Marimuthu, A., Sathe, G. J., Chavan, S., Datta, K. K., Subbannayya, Y., Sahu, A., Yelamanchi, S. D., Jayaram, S., Rajagopalan, P., Sharma, J., Murthy, K. R., Syed, N., Goel, R., Khan, A. A., Ahmad, S., Dey, G., Mudgal, K., Chatterjee, A., Huang, T. C., Zhong, J., Wu, X., Shaw, P. G., Freed, D., Zahari, M. S., Mukherjee, K. K., Shankar, S., Mahadevan, A., Lam, H., Mitchell, C. J., Shankar, S. K., Satishchandra, P., Schroeder, J. T., Sirdeshmukh, R., Maitra, A., Leach, S. D., Drake, C. G., Halushka, M. K., Prasad, T. S., Hruban, R. H., Kerr, C. L., Bader, G. D., Iacobuzio-Donahue, C. A., Gowda, H., and Pandey, A. (2014) A draft map of the human proteome. Nature 509, 575-581
  9. Yadavalli, S., Jayaram, S., Manda, S. S., Madugundu, A. K., Nayakanti, D. S., Tan, T. Z., Bhat, R., Rangarajan, A., Chatterjee, A., Gowda, H., Thiery, J. P. and Kumar, P. (2017). Data-Driven Discovery of Extravasation Pathway in Circulating Tumor Cells. Scientific Reports. 7:43710
  10. Kelkar, D. S., Provost, E., Chaerkady, R., Muthusamy, B., Manda, S. S., Subbannayya, T., Selvan, L. D., Wang, C. H., Datta, K. K., Woo, S., Dwivedi, S. B., Renuse, S., Getnet, D., Huang, T. C., Kim, M. S., Pinto, S. M., Mitchell, C. J., Madugundu, A. K., Kumar, P., Sharma, J., Advani, J., Dey, G., Balakrishnan, L., Syed, N., Nanjappa, V., Subbannayya, Y., Goel, R., Prasad, T. S., Bafna, V., Sirdeshmukh, R., Gowda, H., Wang, C., Leach, S. D., and Pandey, A. (2014) Annotation of the zebrafish genome through an integrated transcriptomic and proteomic analysis. Molecular & cellular proteomics : MCP 13, 3184- 3198
  11. Mitchell, C. J.,# Getnet, D.#, Kim, M. S.#, Manda, S. S., Kumar, P., Huang, T. C., Pinto, S. M., Nirujogi, R. S., Iwasaki, M., Shaw, P. G., Wu, X., Zhong, J., Chaerkady, R., Marimuthu, A., Muthusamy, B., Sahasrabuddhe, N. A., Raju, R., Bowman, C., Danilova, L., Cutler, J., Kelkar, D. S., Drake, C. G., Prasad, T. S., Marchionni, L., Murakami, P. N., Scott, A. F., Shi, L., Thierry-Mieg, J., Thierry-Mieg, D., Irizarry, R., Cope, L., Ishihama, Y., Wang, C., Gowda, H., and Pandey, A. (2015) A multi-omic analysis of human naive CD4+ T cells. BMC systems biology 9, 75
  12. Prasad, T. S., Mohanty, A. K., Kumar, M., Sreenivasamurthy, S. K., Dey, G., Nirujogi, R. S., Pinto, S. M., Madugundu, A. K., Patil A. H., Advani, J., Manda, S. S., Gupta, M. K., Kelkar, D. S., Hall, B., Jiang, X., Peery, A., Rajagopalan, P., Yelamanchi, S. D., Solanki, H. S., Raja, R., Sathe, G. J., Chavan, S., Verma, R., Patel, K. M., Jain, A. P., Syed, N., Datta K. K., Khan, A. A., Dammalli, M., Jayaram, S., Radhakrishnan, A, Mitchell, C. J., Na, C. H., Kumar, N., Sinnis, P., Sharakhov, I. V., Wang. C., Gowda, H., Tu, Z., Kumar, A., Pandey, A. (2017) Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes. Genome Research. 27(1):133-144
  13. Ewing, A. D., Gacita, A., Wood, L. D., Ma, F., Xing, D., Kim, M. S., Manda, S. S., Abril, G., Pereira, G., Makohon-Moore, A., Looijenga, L. H., Gillis, A. J., Hruban, R. H., Anders, R. A., Romans, K. E., Pandey, A., Iacobuzio-Donahue, C. A., Vogelstein, B., Kinzler, K. W., Kazazian, H. H., Jr., and Solyom, S. (2015) Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution. Genome Research 25, 1536-1545
  14. Beachley, V. Z., Wolf, M. T., Sadtler, K., Manda, S. S., Jacobs, H., Blatchley, M. R., Bader, J. S., Pandey, A., Pardoll, D., and Elisseeff, J. H. (2015) Tissue matrix arrays for high-throughput screening and systems analysis of cell function. Nature methods 12, 1197- 1204
  15. Pawar, H., Manda, S. S., Kashyap, M. K., Sathe, G. J., Chavan, S., Singal, M., Manju, H. C., Kumar, K. V. V., Vijayakumar, M., Sirdeshmukh, R., Pandey, A., Prasad, T. S. K., Gowda, H., and Kumar, R. V. (2015) Downregulation of S100 Calcium Binding Protein A9 in Esophageal Squamous Cell Carcinoma. The Scientific World Journal
  16. Li, R., Liao, G., Nirujogi, R. S., Pinto, S. M., Shaw, P. G., Huang, T. C., Wan, J., Qian, J., Gowda, H., Wu, X., Lv, D. W., Zhang, K., Manda, S. S., Pandey, A. and Hayward, S. D. (2015). Phosphoproteomic profiling reveals Epstein-Barr Virus protein kinase integration of DNA damage response and mitotic signaling. PLoS Pathogens. 11:e1005346.
  17. Wu, X., Zahari, M. S., Renuse, S., Nirujogi, R. S., Kim, M. S., Manda, S. S., Stearns, V., Gabrielson, E., Sukumar, S., and Pandey, A. (2015) Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Molecular & cellular proteomics: MCP 14, 2887-2900
  18. Subbannayya, Y., Syed, N., Barbhuiya, M. A., Raja, R., Marimuthu, A., Sahasrabuddhe, N., Pinto, S. M., Manda, S. S., Renuse, S., Manju, H. C., Zameer, M. A., Sharma, J., Brait, M., Srikumar, K., Roa, J. C., Vijaya Kumar, M., Kumar, K. V., Prasad, T. S., Ramaswamy, G., Kumar, R. V., Pandey, A., Gowda, H., and Chatterjee, A. (2015) Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma. Cancer biology & therapy 16, 336-345
  19. Sudha, D., Kohansal-Nodehi, M., Kovuri, P., Manda, S. S., Neriyanuri, S., Gopal, L., Bhende, P., Chidambaram, S. and Arunachalam, J. P. (2017) Proteomic profiling of human intraschisis cavity fluid. Clinical Proteomics 14, 13
  20. Subbannayya, Y., Mir, S. A., Renuse, S., Manda, S. S., Pinto, S. M., Puttamallesh, V. N., Solanki, H. S., Manju, H. C., Syed, N., Sharma, R., Christopher, R., Vijayakumar, M., Veerendra Kumar, K. V., Keshava Prasad, T. S., Ramaswamy, G., Kumar, R. V., Chatterjee, A., Pandey, A., and Gowda, H. (2015) Identification of differentially expressed serum proteins in gastric adenocarcinoma. Journal of proteomics 127, 80-88
  21. Pinto, S. M., Nirujogi, R. S., Rojas, P. L., Patil, A. H., Manda, S. S., Subbannayya, Y., Roa, J. C., Chatterjee, A., Prasad, T. S., and Pandey, A. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-544
  22. Nirujogi, R. S., Wright, J. D., Jr., Manda, S. S., Zhong, J., Na, C. H., Meyerhoff, J., Benton, B., Jabbour, R., Willis, K., Kim, M. S., Pandey, A., and Sekowski, J. W. (2015) Phosphoproteomic analysis reveals compensatory effects in the piriform cortex of VX nerve agent exposed rats. Proteomics 15, 487-499
  23. Murthy, K. R., Rajagopalan, P., Pinto, S. M., Advani, J., Murthy, P. R., Goel, R., Subbannayya, Y., Balakrishnan, L., Dash, M., Anil, A. K., Manda, S. S., Nirujogi, R. S., Kelkar, D. S., Sathe, G. J., Dey, G., Chatterjee, A., Gowda, H., Chakravarti, S., Shankar, S., Sahasrabuddhe, N. A., Nair, B., Somani, B. L., Prasad, T. S., and Pandey, A. (2015) Proteomics of human aqueous humor. Omics : a journal of integrative biology 19, 283-293
  24. Nanjappa, V., Thomas, J. K., Marimuthu, A., Muthusamy, B., Radhakrishnan, A., Sharma, R., Ahmad Khan, A., Balakrishnan, L., Sahasrabuddhe, N. A., Kumar, S., Jhaveri, B. N., Sheth, K. V., Kumar Khatana, R., Shaw, P. G., Srikanth, S. M., Mathur, P. P., Shankar, S., Nagaraja, D., Christopher, R., Mathivanan, S., Raju, R., Sirdeshmukh, R., Chatterjee, A., Simpson, R. J., Harsha, H. C., Pandey, A., and Prasad, T. S. (2014) Plasma Proteome Database as a resource for proteomics research: 2014 update. Nucleic acids research 42, D959-965
  25. Murthy, K. R., Goel, R., Subbannayya, Y., Jacob, H. K., Murthy, P. R., Manda, S. S., Patil, A. H., Sharma, R., Sahasrabuddhe, N. A., Parashar, A., Nair, B. G., Krishna, V., Prasad Ts, K., Gowda, H., and Pandey, A. (2014) Proteomic analysis of human vitreous humor. Clinical proteomics 11, 29
  26. Balakrishnan, L., Nirujogi, R. S., Ahmad, S., Bhattacharjee, M., Manda, S. S., Renuse, S., Kelkar, D. S., Subbannayya, Y., Raju, R., Goel, R., Thomas, J. K., Kaur, N., Dhillon, M., Tankala, S. G., Jois, R., Vasdev, V., Ramachandra, Y., Sahasrabuddhe, N. A., Prasad Ts, K., Mohan, S., Gowda, H., Shankar, S., and Pandey, A. (2014) Proteomic analysis of human osteoarthritis synovial fluid. Clinical proteomics 11, 6
  27. Balakrishnan, L., Bhattacharjee, M., Ahmad, S., Nirujogi, R. S., Renuse, S., Subbannayya, Y., Marimuthu, A., Srikanth, S. M., Raju, R., Dhillon, M., Kaur, N., Jois, R., Vasudev, V., Ramachandra, Y., Sahasrabuddhe, N. A., Prasad Ts, K., Mohan, S., Gowda, H., Shankar, S., and Pandey, A. (2014) Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients. Clinical proteomics 11, 1
  28. Pawar, H., Maharudraiah, J., Kashyap, M. K., Sharma, J., Srikanth, S. M., Choudhary, R., Chavan, S., Sathe, G., Manju, H. C., Kumar, K. V., Vijayakumar, M., Sirdeshmukh, R., Harsha, H. C., Prasad, T. S., Pandey, A., and Kumar, R. V. (2013) Downregulation of cornulin in esophageal squamous cell carcinoma. Acta histochemica 115, 89-99
  29. Marimuthu, A., Subbannayya, Y., Sahasrabuddhe, N. A., Balakrishnan, L., Syed, N., Sekhar, N. R., Katte, T. V., Pinto, S. M., Srikanth, S. M., Kumar, P., Pawar, H., Kashyap, M. K., Maharudraiah, J., Ashktorab, H., Smoot, D. T., Ramaswamy, G., Kumar, R. V., Cheng, Y., Meltzer, S. J., Roa, J. C., Chaerkady, R., Prasad, T. S., Harsha, H. C., Chatterjee, A., and Pandey, A. (2013) SILAC-based quantitative proteomic analysis of gastric cancer secretome. Proteomics Clinical applications 7, 355-366
  30. Marimuthu, A., Chavan, S., Sathe, G., Sahasrabuddhe, N. A., Srikanth, S. M., Renuse, S., Ahmad, S., Radhakrishnan, A., Barbhuiya, M. A., Kumar, R. V., Harsha, H. C., Sidransky, D., Califano, J., Pandey, A., and Chatterjee, A. (2013) Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome. Biochimica et biophysica acta 1834, 2308-2316
  31. Goel, R., Murthy, K. R., Srikanth, S. M., Pinto, S. M., Bhattacharjee, M., Kelkar, D. S., Madugundu, A. K., Dey, G., Mohan, S. S., Krishna, V., Prasad Ts, K., Chakravarti, S., Harsha, H., and Pandey, A. (2013) Characterizing the normal proteome of human ciliary body. Clinical Proteomics 10, 9
  32. Ambekar, A. S., Nirujogi, R. S., Srikanth, S. M., Chavan, S., Kelkar, D. S., Hinduja, I., Zaveri, K., Prasad, T. S., Harsha, H. C., Pandey, A., and Mukherjee, S. (2013) Proteomic analysis of human follicular fluid: a new perspective towards understanding folliculogenesis. Journal of proteomics 87, 68-77
  33. Raju, R., Nanjappa, V., Balakrishnan, L., Radhakrishnan, A., Thomas, J. K., Sharma, J., Tian, M., Palapetta, S. M., Subbannayya, T., Sekhar, N. R., Muthusamy, B., Goel, R., Subbannayya, Y., Telikicherla, D., Bhattacharjee, M., Pinto, S. M., Syed, N., Srikanth, M. S., Sathe, G. J., Ahmad, S., Chavan, S. N., Kumar, G. S., Marimuthu, A., Prasad, T. S., Harsha, H. C., Rahiman, B. A., Ohara, O., Bader, G. D., Sujatha Mohan, S., Schiemann, W. P., and Pandey, A. (2011) NetSlim: high-confidence curated signaling maps. Database : the journal of biological databases and curation 2011, bar032

Book Chapters:

  • Manda, S. S., Michael, D., Jadhao, S. and Nagaraj, S. H. (2019) Functional enrichment - Encyclopedia of Bioinformatics and Computational Biology. 3: 218-229.
  • Sathyanarayanan, A., Manda, S. S., Poojary, M. and Naragaj, S. H. (2019) Exome Sequencing Data Analysis Encyclopedia of Bioinformatics and Computational Biology. 3: 164-179
Dr. Neha Sharma

Dr. Neha Sharma

Research Scientist
Dr. Ruma Pengal

Dr. Neha Sharma

Research Scientist

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Dr. Neha Sharma has a Ph.D. in Lifesciences from ICGEB, New Delhi with expertise in nucleic acid biology. She has vast experience in the field of RNA biology. She has extensively studied small non-coding RNAs, particularly miRNAs and their functional characterization in living systems thereby underpinning their mechanistic roles. She also has patented her work on artificial miRNA-based technology. Her work has been recognized through several first authored publications in peer-reviewed journals. Dr. Neha is the founding team member for a not-for-profit organization, Bioingene, an online platform for webinars and workshops across the world. She is actively involved in co-ordinating the online talks with speakers and performing live interview cum discussion sessions with the invited guests. She was working as a research associate at University of Western Sydney, Australia where she assisted in bulk soil sampling and high throughput nucleic acid extraction from cotton rhizospheres for metagenomics study before joining Karkinos foundation. Currently her research focuses on development and standardization of minimally invasive liquid biopsy techniques in cancer patients for early detection and disease monitoring.

Selected Publications

  1. Neha Sharma and Neeti Sanan-Mishra, Over-expression of a rice specific miRNA, miR820 leads to plant and panicle vigour. Indian Patent Application no.: 361/DEL/2015; published under PCT: PCT/IN2016/050051; publication no: WO2016128998 A1
  2. Neha Sharma, Sudhir Kumar and Neeti Sanan-Mishra (2021) Osa-miR820 regulatory node primes rice plants to tolerate salt stress in an agronomically advantageous manner, BioRxiV (doi:https://doi.org/10.1101/2021.01.20.427536)
  3. Deepti Mittal, Neha Sharma (2018) Fascinating world of next generation sequencing : an overview and its impact on genomics, in Pyrosequencing : Innovations and Applications (edited by: Prerna Pandey), Delve Publishing
  4. Neha Sharma, Deepti Mittal and Neeti Sanan Mishra, (2017) Micro-Regulators of Hormones and Stress, in Mechanism of Plant Hormone Signaling under Stress (ed G. K. Pandey), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118889022.ch29
  5. Deepti Mittal, Neha Sharma, Vinay Sharma, Sudhir K Sopory and Neeti Sanan Mishra (2016) Role of microRNAs in Rice plant under salt-stress. Annals of Applied Biology.doi: 10.1111/aab.12241
  6. Nada Babiker Hamza, Neha Sharma, Anita Tripathi, Neeti Sanan-Mishra, (2016) MicroRNA expression profiles in response to drought stress in Sorghum bicolor, Gene Expression Patterns, Available online 6 January 2016, doi:10.1016/j.gep.2016.01.001
  7. Neha Sharma, Anita Tripathi and Neeti Sanan-Mishra (2015) Profiling the expression domains of a rice-specific microRNA under stress, Frontiers in Plant Science. 6:333. doi: 10.3389/fpls.2015.00333
  8. Neha Sharma, Sandeep Panchal and Neeti Sanan-Mishra (2015) Protocol for artificial microRNA mediated over-expression of miR820 in indica rice, American Journal of Plant Sciences, 12, 6, 1951- 1961. doi: 10.4236/ajps.2015.612196.
Dr. Anindyajit Banerjee

Dr. Anindyajit Banerjee

Head of Bioinformatics
Dr. Anindyajit Banerjee

Dr. Anindyajit Banerjee

Head of Bioinformatics

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As the Head of Bioinformatics at Karkinos Healthcare Pvt. Ltd., Dr. Anindyajit’s professional interests are focused on understanding the genomic landscape of the Indian cancer cohort. His research involves analysing data derived from Whole Genome Sequencing, Targeted Gene Panel Sequencing, and Whole Transcriptomic Sequencing to understand the genomic and transcriptomic alterations that lead to different clinical outcomes in Indian cancer patients. He has experience in analyzing next-generation sequencing data of paediatric acute lymphoblastic leukaemia (ALL) and identifying somatic copy number variations, single nucleotide variations, fusion detection, and gene expression alterations. His goal is to use computational genomic approaches to provide uniform treatment opportunities for patients based on their genetic profiles. During his doctoral training, his research interests were focused on different arms of computational biology like structural biology, network biology, and whole genome analysis.

RESEARCH INTEREST

Computational Genomics

  • Whole genome sequencing
  • Targeted Exome sequencing
  • Whole Transcriptomic analysis

Computational Structural Biology

  • Protein structure prediction
  • Molecular Docking studies
  • High throughput screening of small molecules
  • Molecular Dynamics studies

Sequence Analysis

  • Identification of the important network nodes
  • Node path analysis
  • Pathway analysis

PEER-REVIEWED PUBLICATIONS (as First author)

  1. Banerjee A, Dey S, Chakraborty A, Datta A, Basu A, Chakrabarti S and Datta S. . 2014) Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa Proteins, 82(12):3273-85.
  2. Ahmad B, Banerjee A, Tiwari H, Jana S, Bose S, Chakrabarti S. (2018)Structural and functional characterization of the Vindoline biosynthesis pathway enzymes of Catharanthus roseus. Journal of Molecular Modeling, 24:53.
  3. Das S, Banerjee A, Ali N, Chakrabarti S. (2020) A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential anti-leishmanial drug candidate Journal of Biological Chemistry (Accepted, May 2020)

PEER-REVIEWED PUBLICATIONS (as Co-author)

  1. Das M, Banerjee A, Sarkar S, Majumder J, Chakrabarti S, Jana S. (2020) Amino-alcohol Bioconjugate of Naproxen Exhibits Anti-inflammatory Activity through NF-κB Signaling Pathway. bioRxiv (doi: https://doi.org/10.1101/2020.01.10.901223)
  2. Shadab M, Banerjee A, Sinha R, Das S, Asad M, Kamran M., Maji M, Deepthi M, Jha B, Kumar M, Tripathi A, Kumar B, Chakrabarti S, Ali N. (2019) RNA-seq revealed expression of many novel genes associated with Leishmania donovani persistence and clearance in the host macrophage. Frontiers in Cellular and Infection Microbiology.
  3. Palit S, Mukherjee S, Niyogi S, Banerjee A, Patra D, Chakraborty A, Chakrabarti S, Chakrabarti P, Dutta S. (2018) Quinoline-Glycomimetic Conjugates Reducing Lipogenesis and Lipid Accumulation in Hepatocytes. Chembiochem. Jun 13.
  4. Chauhan J, Dasgupta M, Luthra T, Awasthi A, Tripathy S, Banerjee A, Paul S, Nag D, Chakrabarti S, Chakrabarti G, Sen S. (2018) Design, synthesis and biological evaluation of a novel library of antimitotic C2-aroyl/arylimino tryptamine derivatives that are also potent inhibitors of indoleamine-2, 3-dioxygenase (IDO). Eur J Pharm Sci. Aug 28.
  5. Bhattacharyya D, Hazra S, Banerjee A, Datta R, Kumar D, Chakrabarti S, and Chattopadhyay S. (2016) Transcriptome-wide identification and characterization of CAD isoforms specific for podophyllotoxin biosynthesis from Podophyllum hexandrum. Plant Mol Biol.;92(1-2):1-23.
  6. Chanda SD, Banerjee A, Nandi S, Chakrabarti S, Sarkar MC. (2015) Cordycepin an Adenosine Analogue Executes Anti Rotaviral Effect by Stimulating Induction of Type I Interferon. J Virol Antivir Res; 4:2.
  7. Paul A, Samaddar S, Bhattacharya A, Banerjee A, Das A, Chakrabarti S, DasGupta M. (2014) Gatekeeper tyrosine phosphorylation is autoinhibitory for Symbiosis Receptor Kinase. FEBS Lett, 588(17):2881-9.
  8. Goyal M, Alam A, Iqbal MS, Dey S, Bindu S, Pal C, Banerjee A, Chakrabarti S, Bandyopadhyay U. (2012) Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum. Nucleic Acids Res, 40(3):1174-90.
Dr Asim Joshi

Dr Asim Joshi

Research Scientist
Dr Asim Joshi

Dr Asim Joshi

Research Scientist

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Asim Joshi has completed his PhD from The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) - Tata Memorial Center. He has worked extensively in identifying genetic alterations that contribute to cancer development and therapeutic resistance. He has authored multiple peer reviewed research articles and has presented his work at various scientific conferences. His research interests include cancer genomics and development of novel and innovative cancer diagnostics.

Selected Publications

  1. Joshi A*, Butle A*, Hait S, Mishra R, Trivedi V, Thorat R, Choughule A, Noronha V, Prabhash K, Dutt A. Osimertinib for lung cancer cells harboring low-frequency EGFR T790M mutation. Transl Oncol. 2022 Aug;22:101461. doi: 10.1016/j.tranon.2022.101461. Epub 2022 May 30. PMID: 35653897; PMCID: PMC9156817.
  2. Joshi A*, Mishra R, Desai S, Chandrani P, Kore H, Sunder R, Hait S, Iyer P, Trivedi V, Choughule A, Noronha V, Joshi A, Patil V, Menon N, Kumar R, Prabhash K, Dutt A. Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations. Oncotarget. 2021 Mar 16;12(6):578-588. doi: 10.18632/oncotarget.27905. PMID: 33796225; PMCID: PMC7984830.
  3. Butle A*, Joshi A*, Noronha V, Prabhash K, Dutt A. Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs. Transl Oncol. 2021 Aug;14(8):101111. doi: 10.1016/j.tranon.2021.101111. Epub 2021 May 13. PMID: 33993094; PMCID: PMC8236545.
  4. Desai S, Mishra SV, Joshi A*, Sarkar D, Hole A, Mishra R, Dutt S, Chilakapati MK, Gupta S, Dutt A. Raman spectroscopy-based detection of RNA viruses in saliva: A preliminary report. J Biophotonics. 2020 Oct;13(10):e202000189. doi: 10.1002/jbio.202000189. Epub 2020 Aug 10. PMID: 32609429; PMCID: PMC7361326.
  5. Iyer P, Shrikhande SV, Ranjan M, Joshi A*, Gardi N, Prasad R, Dharavath B, Thorat R, Salunkhe S, Sahoo B, Chandrani P, Kore H, Mohanty B, Chaudhari V, Choughule A, Kawle D, Chaudhari P, Ingle A, Banavali S, Gera P, Ramadwar MR, Prabhash K, Barreto SG, Dutt S, Dutt A. ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer. Int J Cancer. 2019 Apr 15;144(8):2008-2019. doi: 10.1002/ijc.31916. Epub 2018 Dec 8. PMID: 30304546; PMCID: PMC6378102.
Dr. R. Sankaranarayanan

Dr. R. Sankaranarayanan

Director, Preventive Oncology
Dr. R. Sankaranarayanan

Dr. R. Sankaranarayanan

Director, Preventive Oncology

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Rengaswamy Sankaranarayananwas the former Chief of the Cancer Screening Group, Early Detection & Prevention Section and Special Advisor on Cancer Control at the International Agency for Research on Cancer in Lyon, France. He has a MD degree in Radiation oncology followed by post doctoral training in Pittsburgh and Cambridge. After several years of experience in clinical oncology and cancer control in India, Dr Sankaranarayanan joined the International Agency for Research on Cancer (IARC) in 1993. Currently he is serving as a Senior Visiting Scientist at WHO-IARC in Lyon, France. He advises Governments of Tamil Nadu, Kerala in India and several Latin American, Middle-Eastern, South and East Asian and African Governments on cancer prevention, early detection, control and development of efficient, accessible and affordable cancer health services. He is an author in more than 260 papers in international peer-reviewed journals and his manuals on early detection of cervical cancer have been translated into several languages including Chinese, French, Hindi, Portuguese, Russian, Spanish, Thai and Turkish among others

  1. Former Chief of Cancer Screening Group , Early Detection & Prevention Section and Special Advisor on Cancer Control at IARC
  2. Travelled to more than 100 countries and has provided technical support to national cancer programs and human resource development in more than 75 countries
  3. Received several awards for services in cancer control
  4. Advises Govt. of Tamil Nadu, Kerala and several Latin American, MEA, South & East Asian Govts on cancer prevention and early detection
  5. Author of 260+ papers in international peer-reviewed journals
  6. M.D. in radiation oncology, postdoctoral training Pittsburgh and Cambridge
Sripriya Rao

Sripriya Rao

Head, Women Wellness
Sripriya Rao

Sripriya Rao

Head, Women Wellness

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With close to two decades of experience working with the Tata Group, Sripriya has been a trusted strategic advisor and organizational transformation coach for many C-Suite leaders. She worked as Partner and Head for Organisation Change Management for Tata Consultancy Services, managing India, Asia Pacific, Australia and Middle East regions. She is a consistent high performer, recognised as one of the youngest partner and among top twenty five women high performers at Tata Consultancy Services. Sripriya is credited with leading more than fifty highly proficient change teams for large transformation initiatives in Asia Pacific and creating differentiated product offerings and consulting frameworks to manage large scale change in the areas of Next Generation solutions, Enterprise Agility, Digital, Cloud, Robotics and Machine Learning

Among her many successful transformation stories, Sripriya led a consulting team to help transform Wealth Management platform – integrating front to back office operations. Similarly, she helped modernise the IT platform for Department of Posts, India across 23 postal circles. Sripriya received her B.E. degree in Electronics and Communication from NMAM Institute of Technology and is a CTT certified consultant at Barett Values Centre on Leadership values assessment and culture

  1. Ex-Partner & Head for Organisational Change Management, Tata Consultancy Services (TCS), managing Asia+ region
  2. One of the youngest partners and was among the top 25 TCS women achievers in TCS Leadership Program
  3. Led over 50 large scale business initiatives across 14+ countries with clients such as JLR, UBS, GE Healthcare Financial Services, Petronas, Ericsson and more.
  4. Helped modernize the IT platform for Department of Posts, India across 23 postal circles impacting 500K+ employee base