Dr. Ruma Pengal

Senior Research Scientist

Dr. Ruma Pengal has a background in cellular biology with a keen interest in signal transduction pathways. She has worked on research projects involving signalling in innate immune cells and kinase pathways involved in cellular injury.

Selected peer-reviewed publications (Ruma)

  1. Nie X, Chanley MA, Pengal R, Thomas DB, Agrawal S, Smoyer WE. Pharmacological and genetic inhibition of downstream targets of p38 MAPK in experimental nephrotic syndrome. Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F602-F613. doi: 10.1152/ajprenal.00207.2017.
  1. Guess AJ, Ayoob R, Chanley M, Manley J, Cajaiba MM, Agrawal S, Pengal R, Pyle AL, Becknell B, Kopp JB, Ronkina N, Gaestel M, Benndorf R, Smoyer WE. Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis. PLoS One. 2013;8(1):e54239. doi: 10.1371/journal.pone.0054239
  2. Pengal R, Guess AJ, Agrawal S, Manley J, Ransom RF, Mourey RJ, Benndorf R, Smoyer WE. Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury. Am J Physiol Renal Physiol. 2011 Sep;301(3):F509-19.
  3. Pengal RA, Ganesan LP, Wei G, Fang H, Ostrowski MC, Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol Immunol. 2006 Apr;43(10):1557-64.
  4. Fang H, Pengal RA*, Cao X, Ganesan LP, Wewers MD, Marsh CB, Tridandapani S. Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP. J Immunol. 2004 Jul 1;173(1):360-6 (*- Co-first author)