Prasanth Ariyannur

Senior Research Scientist

Dr. Prasanth Ariyannur is the head of clinical genomics laboratory at Karkinos Advanced Cancer DIagnostics and Research (ACCDR) Laboratory at Kochi. He got his MBBS from Govt. Medical College Thiruvananthapuram and MD in Clinical Biochemistry and laboratory medicine from Amrita School of Medicine. In 2004, he went for graduate studies and trained in Uniformed Services University of Health Sciences (USUHS), Bethesda Maryland USA. His training was in molecular neurobiology on addiction physiology, neuronal energetics and tryptophan mediated immune tolerance in the US National Capital Consortium, the US National Institute of Health and USUHS. He has identified and characterized the gene responsible for aspartyl N-acetyltransferase function in the brain and generated transgenic animal models for studying the biobehavioral effects in 2011. During the last decade, Dr. Prasanth has been instrumental in establishing research projects to understand the genotype and phenotype correlation of many hereditary cancers such as Neurofibromatosis and other RASopathies, hereditary breast and ovarian cancers and hereditary colon cancers in Amrita Institute of Medical Sciences, Kochi Kerala. He established a diagnostic molecular oncology laboratory in Amrita Institute, Kochi. He has been actively involved in somatic mutation identification and constantly improving the genomic analysis methods in cancers occurring in lung, breast, prostate, colon, thyroid and endometrium. He has developed many novel laboratory tests in Amrita Institute which got national and international quality accreditations. He has 35 publications in international journals on basic science research, along with review articles and book chapters. He is also a principal Investigator of a project funded by ICMR.

Selected peer-reviewed publications (Dr. Prasanth Ariyannur)

  1. Ariyannur PS, Joy R, Menon V, Paulose R, Pavithran K, Vasudevan DM. An approach to compare Nanostring PanCancer pathway analysis with TCGA data for colon adenocarcinoma in the South Indian population: A pilot study. Ecancermedicalscience 2021;15 1302. PMID: 34824625.
  2. Mohan AA, Vallonthaiel AG, Nambiar A, Ariyannur P, Joy RA, Thelakkattusserry SK, Vikkath N, Joseph T, Mehta A, Perathur A. EGFR analysis on scrapings from cytology smears in lung carcinoma, an effective alternative to testing on trucut biopsies. Diagn Cytopathol. 2021, 49(10):1155-1163. PMID: 34432954.
  3. Paul A, Pai, PG, Ariyannur PS, Joy RA. Diagnostic accuracy of MicroRNA 208b level with respect to different type of atrial fibrillation. Indian Heart J 2021, 73(4):506-510. PMID: 34474768
  4. Joy RA, Thelakkattusserry SK, Vikkath N, Bhaskaran R, Vasudevan D, Krishnan S, Ariyannur PS. Somatic mutation detection efficiency in EGFR: a comparison between High Resolution Melting Analysis and Sanger Sequencing. BMC Cancer, 2020 September 22;20(1):902. PMID: 32962681.
  5. Vikkath, N, Ariyannur PS, Menon KN, Bindhu MR, Pillai A., Exploring the role of defective fibronectin matrix assembly in the VHL-associated CNS hemangioblastoma. Drug Metabolism and Personalized Therapy., 2018 September;33(3):127-134. PMID: 29813026 .